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Test Code DRV1 Dilute Russell's Viper Venom Time (DRVVT), Plasma


Additional Testing Requirements


Serum anticardiolipin antibody testing (CLPMG / Phospholipid [Cardiolipin] Antibodies, IgG and IgM, Serum) and anti-beta-2 glycoprotein I (B2GMG / Beta-2 Glycoprotein 1 Antibodies, IgG and IgM, Serum) antibody testing should also be performed in conjunction with coagulation-based testing for lupus anticoagulant to enhance detection of different types of antiphospholipid antibodies.



Specimen Required


Only orderable as part of a profile or reflex. For more information see:

ALUPP / Lupus Anticoagulant Profile, Plasma

AATHR / Thrombophilia Profile, Plasma and Whole Blood

APROL / Prolonged Clot Time Profile, Plasma

ALBLD / Bleeding Diathesis Profile, Limited, Plasma

ADIC / Disseminated Intravascular Coagulation/Intravascular Coagulation and Fibrinolysis (DIC/ICF) Profile, Plasma


Useful For

Detecting and confirming or helping to exclude the presence of lupus anticoagulants (LA)

 

Identifying LA that do not prolong the activated partial thromboplastin time (APTT)

 

Evaluating unexplained prolongation of the APTT or prothrombin time clotting tests

 

Distinguishing LA from a specific coagulation factor inhibitor or coagulation factor deficiencies

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
DRV2 DRVVT Mix No No
DRV3 DRVVT Confirmation No No

Testing Algorithm

If dilute Russell's viper venom time (DRVVT) ratio is ≥1.20, then DRVVT mix and DRVVT confirmation will be performed at an additional charge.

Method Name

Only orderable as part of a profile or reflex. For more information see:

ALUPP / Lupus Anticoagulant Profile), Plasma

AATHR / Thrombophilia Profile), Plasma and Whole Blood

APROL / Prolonged Clot Time Profile, Plasma

ALBLD / Bleeding Diathesis Profile, Limited, Plasma

ADIC / Disseminated Intravascular Coagulation/Intravascular Coagulation and Fibrinolysis (DIC/ICF) Profile, Plasma

 

Optical Clot-Based

Reporting Name

Dilute Russells Viper Venom Time, P

Specimen Type

Plasma Na Cit

Specimen Stability Information

Specimen Type Temperature Time Special Container
Plasma Na Cit Frozen 14 days

Reference Values

Only orderable as part of a profile or reflex. For more information see:

ALUPP / Lupus Anticoagulant Profile, Plasma

AATHR / Thrombophilia Profile, Plasma and Whole Blood

APROL / Prolonged Clot Time Profile, Plasma

ALBLD / Bleeding Diathesis Profile, Limited, Plasma

ADIC / Disseminated Intravascular Coagulation/Intravascular Coagulation and Fibrinolysis (DIC/ICF) Profile, Plasma

 

< 1.20

Normal ranges for children: not clearly established, but similar to normal ranges for adults, except for newborn infants whose results may not reach adult values until 3 to 6 months of age.

Day(s) Performed

Monday through Friday

Report Available

1 to 4 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

85613-DRVVT

85613-DRVVT mix (if appropriate)

85613-DRVVT confirmation (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
DRV1 Dilute Russells Viper Venom Time, P 15359-3

 

Result ID Test Result Name Result LOINC Value
RVR1 DRVVT Screen Ratio 15359-3

Specimen Minimum Volume

See Specimen Required