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Test Code PBCPN Primary Biliary Cholangitis Antibody Panel, Serum


Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 1.5 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Useful For

Evaluation of at-risk or previously diagnosed primary biliary cholangitis patients with new features of other liver diseases or systemic autoimmune diseases

Profile Information

Test ID Reporting Name Available Separately Always Performed
NAIFA Antinuclear Ab, HEp-2 Substrate, S Yes Yes
SP100 SP100 Antibody, IgG, S Yes Yes
GP210 GP210 Antibody, IgG, S Yes Yes
AMA Mitochondrial Ab, M2, S Yes Yes

Method Name

GP210, SP100: Enzyme-Linked Immunosorbent Assay (ELISA)

AMA: Enzyme Immunoassay (EIA)

NAIFA: Indirect Immunofluorescence

Reporting Name

PBC Comprehensive Antibody Panel, S

Specimen Type

Serum

Specimen Minimum Volume

1.1 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 21 days
  Frozen  21 days

Reference Values

MITOCHONDRIAL AB, M2

Negative: <0.1 Units

Borderline: 0.1-0.3 Units

Weakly positive: 0.4-0.9 Units

Positive: ≥1.0 Units

Reference values apply to all ages.

 

SP100 Antibody, IgG

Negative: ≤20.0 Units

Equivocal: 20.1-24.9 Units

Positive: ≥25.0 Units

 

GP210 Antibody, IgG

Negative: ≤20.0 Units

Equivocal: 20.1-24.9 Units

Positive: ≥25.0 Units

 

ANTINUCLEAR AB, HEP-2 SUBSTRATE

Negative: <1:80

Day(s) Performed

Tuesday

Report Available

2 to 8 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

86039

83516 x2

86381

LOINC Code Information

Test ID Test Order Name Order LOINC Value
PBCPN PBC Comprehensive Antibody Panel, S 106054-0

 

Result ID Test Result Name Result LOINC Value
AMA Mitochondrial Ab, M2, S 51715-1
ANAH Antinuclear Ab, HEp-2 Substrate, S 59069-5
SP100 SP100 Antibody, IgG, S 96565-7
GP210 GP210 Antibody, IgG, S 96560-8
1TANA ANA Titer: 33253-6
1PANA ANA Pattern: 49311-4
2TANA ANA Titer 2: 33253-6
2PANA ANA Pattern 2: 49311-4
CYTQL Cytoplasmic Pattern: 55171-3
LCOM Lab Comment: 77202-0

Forms

If not ordering electronically, complete, print, and send a Gastroenterology and Hepatology Test Request (T728) with the specimen.